The Biggest Screwups That Changed History
The Biggest Screwups That Changed History

The Biggest Screwups That Changed History

Khalid Elhassan - April 29, 2023

The Biggest Screwups That Changed History
Alexander Fleming in his lab. Newcastle University

The Mistake that Saved Millions of Lives

Alexander Fleming (1881 – 1955) was an unprepossessing Scottish doctor, pharmacologist, and microbiologist. Until 1928, there had been little in his decades-long career to indicate that he would revolutionize medicine and save millions of lives worldwide. Until that year, his greatest career accomplishment had to do with research on enzymes. Then Fleming discovered penicillin, the antibiotic that revolutionized medical care and saved millions of lives from fatal bacterial infections. It happened by accident, because of sloppiness and a basic mistake.

Lucky breaks followed Fleming his whole life. Born in Scotland, he moved to London, where he graduated high school before he got a job in a shipping office. That might have become his career, but an uncle died four years later, and left Fleming an inheritance that allowed him to go to medical school. He initially wanted to become a surgeon, but while serving in a reserve regiment, he was recognized as a great marksman. To become a surgeon, he would have had to leave his medical school and move away – which would have meant leaving his unit. His commanding officer did not want to lose the promising reservist. So he introduced Fleming to a prominent researcher and immunologist, who convinced him to become a researcher instead.

The Biggest Screwups That Changed History
Alexander Fleming in his lab. Time Magazine

A Sloppy Lab That Revolutionized Medicine

Alexander Fleming served in the Army Medical Corp in World War I, and observed the deaths of many soldiers from uncontrollable infections. Antiseptics were used to fight infections, but they often did more harm than good. Fleming conducted research, which showed that the use of antiseptics was a mistake when it came to serious injuries: they did not stop the proliferation of anaerobic bacteria in deep wounds. His research was initially rejected, but Fleming plugged on. One day in 1922, while he battled a cold, Fleming transferred some of his snot to a Petri dish. A slob, he put it on his cluttered desk, then forgot it for a couple of weeks. When he finally remembered and examined it, the Petri dish was full of bacterial colonies.

However, the microscope revealed that one area of snot was free of bacteria. Further examination revealed that it was due to the presence of an enzyme, which he called lysozyme, which had some antimicrobial properties. That laid the groundwork for his discovery of penicillin. In 1928, Fleming, still a lab slob, left an uncovered Petri dish next to an open window, where it became contaminated with fungus spores. When he checked it under the microscope, Fleming discovered that the bacteria near the fungus were dying. He managed to isolate the fungus, and discovered that it was effective against numerous pathogens that caused diseases such as pneumonia, meningitis, diphtheria, scarlet fever, gonorrhea, and many more. Thus, penicillin was discovered. As Fleming put it: “I did not discover penicillin. Nature did that. I only discovered it by accident“.

The Biggest Screwups That Changed History
Spinach was not the super food that Popeye led generations of children to believe. Imgur

The Typographical Mistake That Created the Spinach Super Food Myth

Many kids who watched Popeye the Sailor Man have dreamt that they might gain super powers if they could only overcome their distaste for spinach. Popeye’s love of spinach was popularized to a receptive public, primed by a widespread belief that spinach was extraordinarily beneficial. Sadly, kids who mastered their gag reflexes long enough to swallow the green stuff were not rewarded with an explosive increase in strength, prowess, or other abilities and talents. There was an upside, though, as the kids learned a vital life lesson: don’t believe everything you see on TV.

Popeye’s passion for spinach, as well as the popular faith in its exceptional qualities, was caused by a simple math mistake. In 1870, German scientist Erich von Wolf was conducting research into the amount of iron in Spinach and other vegetables, and discovered that spinach had an iron content of 3.5 milligrams per 100 gram serving. However, when Wolf wrote up his findings, he made a mistake and misplaced a decimal point. As a result, he put down spinach’s iron content as ten times greater than what it actually was: 35 milligrams of iron per 100 gram serving, instead of 3.5 milligrams. It was not until 1937 that somebody double checked Wolf’s math, and spotted the mistake. By then, Popeye was already a cultural icon, and the spinach myth had taken hold.

The Biggest Screwups That Changed History
Model of Herod’s Temple. Wikimedia

Mooning This Particular Crowd Might Have Been a Mistake

Just as a jet engine turns fuel into a loud roar, we create farts by converting undigested food in our lower colon into intestinal gas. We then blow that gas through a narrow opening, the butthole, which is surrounded by fatty flaps and folds. As the gas exits, those flaps and folds vibrate, creating a fleshy clamor – the fart. Oddly, over 99% of our farts does not smell. On average, a fart is 59% nitrogen, 21% hydrogen, 9% carbon dioxide, 7% methane, and 4% oxygen – all of which are odorless. However, a minute fraction of less than 1% is made up of other stuff such as ammonia, hydrogen sulfide, and skatole (from the Greek skatos, meaning… the less appropriate word for poop) that seriously stinks.

Stinks so bad, in fact, that people can smell fart particles even when they comprise only 1 part per 100 million parts of air. Not all farts are the same, and some are way worse than others. Take history’s deadliest, which was let go around the time of Passover in 44 AD, in Jerusalem, not long after the death of King Herod Agrippa. As thousands of Jews gathered to partake in the Passover feast and festivities, a Roman soldier stationed above the temple turned around, bared his butt, mooned the crowd, and cut a fart. As seen below, that turned out to be a mistake.

The Biggest Screwups That Changed History
A first century AD bust believed to be that of Josephus. Gertjan Glismeijer

The Fart That Started a Riot

Understandably, the religious crowd below did not take kindly to the blasphemous insult in the temple. The Jews erupted into riots, and the Romans rushed in soldiers to quell the disturbances. Things escalated, and by the time the dust settled, about 10,000 people lay dead – all because of a chain of events that started with a fart. As seen below, First century AD Jewish historian Flavius Josephus left posterity an account of the lethal flatulence. As he described how the disturbance began:

The Jews’ ruin came on, for when the multitudes were come together to Jerusalem, to the feast of unleavened bread, and a Roman cohort stood over the cloisters of the temple (for they always were armed and kept guard at the festivals, to prevent any innovation which the multitude thus gathered together might take), one of the soldiers pulled back his garment, and cowering down after an indecent manner, turned his breech [bum] to the Jews, and spoke such words as you might expect at such a posture. At this the whole multitude had indignation, and made a clamor to Cumanus [the provincial Roman procurator], that he would punish the soldier; while the rasher part of the youth, and such as were naturally the most tumultuous, fell to fighting, and caught up stones, and threw them at the soldiers“. Things got worse.

The Biggest Screwups That Changed History
Ambush and destruction of a Roman column by Jewish insurgents. Pinterest

History’s Most Lethal Fart?

Because one Roman soldier thought it would be funny to troll a crowd, thousands died. The poor taste of that one anonymous legionary was the start of a bout of widespread violence and a weird chain of events the led to mass deaths. Things escalated quickly, as the Romans, never known for a light touch when dealing with disturbances in their provinces, came down hard on the Jews. As Josephus continued his account, when the Roman procurator heard of the rioting in Jerusalem:

Cumanus was afraid lest all the people should make an assault upon him, and sent to call for more men, who, when they came in great numbers into the cloisters, the Jews were in a very great consternation. Being beaten out of the temple, they ran into the city; and the violence with which they crowded to get out was so great, that they trod upon each other, and squeezed one another, till ten thousand of them were killed, insomuch that this feast became the cause for mourning to the whole nation, and every family lamented“. It was thus history’s deadliest fart.

The Biggest Screwups That Changed History
Gunter Schabowski giving the speech that brought down the Berlin Wall. YouTube

The Mistake that Brought Down the Berlin Wall

The Berlin Wall stood for decades as both a literal dividing line, and the Cold War’s ultimate symbolic separator, marking off a dour communist east from a vibrant capitalist west. There was a reason why Ronald Reagan’s admonition in speech delivered during a 1987 visit to West Berlin, “Mister Gorbachev, tear down this wall!” resonated so well back then. At the time, few could have predicted that, little more than two years later, the Berlin Wall would come down with such suddenness so as to catch politicians and pundits alike off guard. And it came down because a bureaucrat made a mistake.

The Biggest Screwups That Changed History
Fall of the Berlin Wall. International Policy Digest

In the late 1980s, communism began to crumble in the Soviet Union and Eastern Europe, and East Germany’s communist leaders began to grudgingly ease their citizens’ travel restrictions. On November 9th, 1989, East Berlin’s communist party boss Gunter Schabowski held a press conference to explain some minor revisions to the travel code. However, he flubbed it, and mistakenly implied that travel restrictions were being completely removed. When a reporter asked when the changes would take effect, Schabowski shrugged and replied: “immediately, right away“. That hit the news, and when East Germans heard it, they swarmed the border, demanding the promised free passage. The border guards had received no such instructions, but rather than deal with a riot, they stepped aside, and the wall came down in a rapturous celebration – Berlin’s greatest citywide party, ever.

The Biggest Screwups That Changed History
Churchill, Truman, and Stalin at Potsdam, where they issued a joint declaration that demanded Japan’s immediate and unconditional surrender. Atomic Heritage

Japan Was Nuked Because of a Translation Mistake

After World War II, a myth grew that the atomic bombing of Japan was unnecessary because Japan was on her last legs, and about to surrender. Supposedly, the Allies simply had to blockade Japan, and the Japanese government would have given in. That might have worked if the war had been confined to the Japanese home islands, where the Japanese could have been isolated. Unfortunately, both for the Japanese and for hundreds of millions of conquered subjects in Japanese occupied territory, that was not the case. At war’s end Japan still held an extensive empire in the Pacific and Asia, in which hundreds of millions were forced to endure a barbaric occupation. Additionally, millions of Japanese soldiers were still fighting Allied forces in China, Burma, and in the Pacific.

Whether or not the Japanese homeland was blockaded, the war still went on beyond Japan. Also, the Japanese held hundreds of thousands of Allied POWs, and subjected them daily to brutal treatment. In short, every day the war continued was another day in which millions suffered, and in which thousands more became casualties. From that perspective, it was not a mistake for America and her allies to treat Japan as a formidable foe who was inflicting significant harm every day, and who would continue to do so indefinitely if not stopped. As far as the Allies were concerned, Japan was a menace that had to he put down ASAP. However, a simple translation mistake might have determined when and how the US put Japan down, and led to the decision to drop atomic bombs on Hiroshima and Nagasaki.

The Biggest Screwups That Changed History
Atomic mushroom cloud over Hiroshima. Atomic Archive

A Momentous Translation Mistake

What might have been the most momentous translation mistake in history began with the Proclamation Defining Terms for Japanese Surrender. Also known as the Potsdam Declaration, it was issued by the Allies on July 26th, 1945. America, which had successfully tested the atomic bomb ten days earlier, along with her allies, issued a blunt statement calling for the surrender of all Japanese armed forces. It was an ultimatum that warned Japan to surrender immediately. Otherwise, it would faceprompt and utter destruction. The terms were hotly debated within the Japanese government.

Eventually, Prime Minister Kantaro Suzuki stated at a press conference that Japanese policy towards the Potsdam Declaration would be one of “mokusatsu“. It was a Japanese word which meant that he had received the message, and was giving it serious consideration. Unfortunately, Japanese is a subtle language – sometimes too subtle – in which the same word could convey a variety of meanings. Another meaning for mokusatsu is to “contemptuously ignore”, and that was the meaning the translators gave President Truman. Ten days later, the Enola Gay flew from Tinian to drop an atomic bomb on Hiroshima.

The Biggest Screwups That Changed History
Dr. Robert Liston. Hill & Adamson

Speed Kills – In the Operating Room

Bad doctors and medical screw-ups are all too common. Indeed, thanks to negligent or outright incompetent medical professionals, there is a thriving field in the legal profession that focuses solely on medical malpractice. Fortunately for Dr. Robert Liston (1794 – 1847) of London, he practiced in an era when, and in a country where, medical malpractice litigation was not as big as it is today in the US. If not, medical malpractice lawyers would have had a field day suing him for that one time he managed to kill three people during a single surgery – two of whom were not even his patients.

Dr. Liston was a surgeon known for his speed. In the days before the use of anesthetics had become as widespread as today, an ability to operate speedily was a decided plus. It meant that patients spent less time enduring excruciating pain as a surgeon cut into them. It also increased the odds of survival, lessening the odds of patients going into shock, as well as reducing the time in which their vitals were exposed to germs and other vectors of infection.

The Biggest Screwups That Changed History
Dr. Robert Liston. Art UK

History’s Deadliest Surgery?

Dr. Liston was famous for his ability to complete operations in a matter of seconds, and to amputate a leg in just two and a half minutes. Unsurprisingly, chances for a mistake were pretty high. Dr. Liston played up his reputation for speedy surgery for all it was worth. Surgeries back then were spectator events, and observers watched what was going on from galleries that surrounded operating rooms. As he brandished his cutting tools, Dr. Liston would often shout to the audience “time me, gentlemen!It became his catchphrase.

During one surgery to amputate a leg, Dr. Liston accidently severed the fingers off the hand of an assistant who was holding down the patient’s leg. Liston continued with the job, and took off the patient’s leg. Both patient and assistant got gangrene, and died within a few days. In his frenzied slicing, Dr. Liston also accidentally cut an elderly spectator’s coat. The old man was not hurt, but he was splattered with blood from patient’s amputated leg and the medical assistant’s severed fingers. Thinking that he had been wounded, the elderly spectator panicked, had a heart attack, and died.

The Biggest Screwups That Changed History
The death of Francois Vatel. Pinterest

The Mistake that Made a Master Chef Kill Himself

French master chef Francois Vatel was put in charge of a grand banquet for 2,000 people, scheduled at the Chateau de-Chantilly for April 25th, 1671, in honor of King Louis XIV. The banquet was scheduled on short notice, and Vatel, who had only fifteen days to prepare, got stressed out by a series of minor mishaps. During a preliminary dinner a few days before the banquet, there were more guests than expected, and two out of twenty six tables went without roast. That minor mistake mortified Vatel, and he wept that he had lost honor and could not bear the shame. Reassurances that the dinner had gone great, and that the king was pleased, did not comfort Vatel, who continued to obsess about the roast-less tables. Later that night, a grand display of fireworks flopped because fog and low clouds descended, which depressed Vatel even further.

Early the following morning, April 24th, one day before the banquet, Vatel encountered a supplier bringing two loads of fish, and asked him if that was all. The supplier, unaware that Vatel was referring to all fish from all suppliers, not just himself, replied that it was. That was the final straw for a frazzled Vatel, who had hardly slept for two weeks. He broke down, crying “I won’t survive this insult. My honor and reputation are at stake!” Unable to endure what he was sure would be a humiliation when the royal banquet turned into a flop, Vatel took a sword and ran himself through. As it turned out, it did not take long before the misunderstanding resolved itself, as fish from other suppliers began to arrive soon thereafter. As the master chef lay dying of his wound, wagon loads of fish trundled their way into the Chateau de-Chantilly.

The Biggest Screwups That Changed History
Cuban exiles train in preparation for the Bay of Pigs invasion. Imgur

A Time Zone Mistake Doomed an Invasion

In everyday life for most of us, a failure to correctly set the time, like when daylight savings come around or roll away, can lead to minor inconveniences. Things along the lines of showing up for work an hour late or an hour early. However, a failure to correctly set the time when there is fighting to do, can lead to disaster. Such was the case in the spring of 1961, as American-trained Cuban exiles readied themselves to overthrow Fidel Castro.

The Cuban exiles were convinced – or more accurately, they convinced themselves – that when they landed in Cuba, they would be supported by the US Air Force, with the US Marines right behind them. The aerial cover actually promised the Cuban exiles by the CIA was support from 16 WWII era B-26 medium bombers, flying out of bases in Nicaragua. However, that number was halved to 8 bombers when the new president, JFK, insisted that the operation be kept minimal.

The Biggest Screwups That Changed History
Cuban exiles captured in the failed Bay of Pigs invasion. Pinterest

The Farcical Collapse of an Invasion

Cuban exiles landed on the Bay of Pigs on April 17th, 1961, but the 8 B-26s turned out to be woefully inadequate support. Pinned down, with their backs to the sea, no means of retreat, and no chance to advance into Cuba’s interior, the invaders were cut to pieces. The invasion had failed, but on the following day, JFK made a final gesture. With Castro’s forces now on full alert, any followup strikes by the B-26s would require fighter protection.

So the president authorized 6 fighter jets from the aircraft carrier USS Essex to fly cover over the Bay of Pigs for an hour on April 18th, to protect the B-26s as they carried out another strike. However, the invasion, which had already gone from failure to fiasco, was destined to conclude with a farce. The rendezvous between the carrier jets and the B-26s was missed. The Pentagon had failed to factor in the one hour time zone difference between the bombers’ base in Nicaragua and Cuba.

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Where Did We Find This Stuff? Some Sources and Further Reading

American College of Surgeons – Time Me, Gentlemen! The Bravado and Bravery of Robert Liston

Atlantic, The, October 24th, 2012 – ‘Time Me Gentlemen’: The Fastest Surgeon of the 19th Century

Business Insider, June 16th, 2017 – Spinach Doesn’t Have As Much of a Key Nutrient Needed in Your Blood as You Might Think

Cracked – 12 Tiny Things That Changed the Course of History

Daily Beast – How a Fart Killed 10,000 People

Daily Mail, July 3rd, 2013 – Sorry Popeye, Spinach DOESN’T Make Your Muscles Big: Expert Reveals Sailor’s Love of the Food Was Due to a Misplaced Decimal Point

Dawson, Jim – Who Cut the Cheese? A Cultural History of the Fart (1998)

Ere Now – Some Mistakes Have Turned Out Well: Math Error, 1492

Extreme Tech – Tech Wrecks: Lessons From Some of the Biggest Hardware Screwups

Folk Texts – Breaking Wind: Legendary Farts

Grunge – The Fart That Caused 10,000 Deaths

Guardian, The, August 29th, 2007 – Key That Could Have Saved the Titanic Goes Up for Auction

Healio – Penicillin: An Accidental Discovery Changed the Course of Medicine

History Collection – 20 Mistakes the Axis Powers Made in World War II

History News Network – Failures of the Presidents: JFK’s Bay of Pigs Disaster

How Stuff Works – 5 Reasons Why the Bay of Pigs Invasion Failed

IEEE Spectrum – Columbus’s Geographical Miscalculations: Columbus Based his ‘Enterprise of the Indies’ on Three Massive Metrological Errors

Motley Fool – How Coke Helped Create Pepsi, and Other Historic Market Moments

National Security Agency – Mokusatsu: One Word, Two Lessons

Nescafe – What is Decaf Coffee?

New York Times, November 2nd, 2015 – Gunter Schabowski, Whose Gaffe Helped Burst the Berlin Wall, Dies at 86

Pangeanic – The Worst Translation Mistake in History

Searching in History – Tragic Death of Francois Vatel

Telegraph, The, August 29th, 2007 – Key That Could Have Saved the Titanic

Time Magazine, September 28th, 2015 – How Being a Slob Helped Alexander Fleming Discover Penicillin

UK Tea & Infusions Association – The Humble Tea Bag

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