25. A Byzantine Pandemic that Rivaled the Black Death

The Black Death, history’s most famous pandemic, was also its deadliest. However, Justinian’s Plague, 541 – 542 AD, gives it a run for its money in lethality and consequences. It was named after Emperor Justinian I, during whose reign it and the aforementioned Nika Riots occurred. Justinian actually came down with the plague named after him, but survived.
It is history’s first recorded pandemic, because it swept across three continents, Europe, Asia, and Africa. Like the Black Death, Justinian’s Plague was caused by the Yersinia pestis bacterium. It was also transmitted by infected fleas, carried by black rats. Also like the Black Death, Justinian’s Plague struck with a devastating initial outbreak, followed by several recurrences in succeeding years. By the time the last recurrence ended, the plague had killed an estimated 25 million to 100 million people.



