From the shadowy streets of Prohibition-era Chicago to the gritty neighborhoods ruled by modern syndicates, criminal gangs have shaped American history in profound ways. Their stories are woven into the fabric of cities, influencing politics, culture, and law enforcement. With notorious leaders like Al Capone and ruthless organizations such as MS-13, these groups have left an indelible mark, fueling both fear and fascination. This article delves into the origins, evolution, and enduring legacy of America’s most infamous gangs—unveiling the power struggles, violence, and resilience that define their legacy.