Some disasters are so cataclysmic that their effects transcend geography and time. These events don’t just devastate local communities—they reshape global politics, economies, and even cultures. From pandemics to industrial accidents, their aftershocks have altered the course of history, sparking international cooperation, conflict, and innovation. Understanding these disasters reveals how deeply interconnected our world truly is. As we revisit 15 of the most influential disasters, we’ll see how each left a legacy felt far beyond its original epicenter, influencing generations to come.